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Follistatin-344 Peptide Steroid Hormones Inhibits Follicle-Stimulating Hormone Release

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Changsha Zhenxiang Biotechnology Co., Ltd.
City: Changsha
Province/State: Hunan
Country/Region: China
Tel: 00-86-13397492710
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Follistatin-344 Peptide Steroid Hormones Inhibits Follicle-Stimulating Hormone Release

Place of Origin : China
Brand Name : YC
Certification : HSE, ISO 9001, USP, BP
MOQ : Negotiable
Price : Negotiable
Packaging Details : As you require
Delivery Time : 12 hours within your payment is received
Payment Terms : T/T, Western Union, Money Gram, Bitcoin
Supply Ability : 1000kg/month
Follistatin (FST) is : a secreted glycoprotein
that was first identified as : a follicle­stimulating hormone inhibiting substance
in : ovarian follicular fluid (1, 2)
CAS No. : 307297-39-8
follistatin can inhibit : the activity of other TGF-Beta ligands
including : BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-Beta1
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Follistatin-344 Peptide Steroid Hormones Inhibits Follicle-Stimulating Hormone Release

Follistatin (FST) is a secreted glycoprotein that was first identified as a follicle­stimulating hormone inhibiting substance in ovarian follicular fluid (1, 2). Human Follistatin cDNA encodes a 344 amino acid (aa) protein with a 29 aa signal sequence, an N­terminal atypical TGF binding domain, three Follistatin domains that contain EGF­like and kazal­like motifs, and a highly acidic C­terminal tail.


Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-Beta ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-Beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin is a 37.8 kDa protein containing 344 amino acids.



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